Comparison of the effect of haloperidol versus dexmedetomidine in the prevention of delirium after cardiac surgery
Phase 3
Recruiting
- Conditions
- Delirium.Other delirium
- Registration Number
- IRCT20080830001127N9
- Lead Sponsor
- Tabriz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 180
Inclusion Criteria
All adult patients 18 up to 75 years old , candidates of elective cardiac surgery with cardiopulmonary bypass
Exclusion Criteria
History of previous CVA without full recovery for 5 years - emergency procedures - death in ICU
Emergency surgeries
Death in ICU
Patients under 18 years old and over 75 years old
History of neurological and mental diseases or taking antipsychotic drugs
Not using cardiopulmonary bypass
Allergy to haloperidol or dexmedetomidine
Dementia
QTc interval greater than 500 ms or complete heart block
History of malignant neuroleptic syndrome
Bradycardia
Liver and kidney diseases
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Delirium. Timepoint: during ICU stay. Method of measurement: CAM–ICU measurement tool.
- Secondary Outcome Measures
Name Time Method Duration of need to mechanical ventilation. Timepoint: During hospitalization in ICU. Method of measurement: Counting the number of hours of mechanical ventilation in the ICU.;Length of stay in ICU. Timepoint: Reviewing the patient ICU records. Method of measurement: Counting the number of days of ICU stay.;Mortality. Timepoint: During hospitalization in ICU. Method of measurement: Reviewing the patient ICU records.