Effects of Dietary Pork and Egg on Appetite, Meal-patterning, and Weight Loss in Men

Not Applicable

Completed

• Conditions: Weight Loss
• Interventions: Other: Energy Restriction

• Registration Number: NCT00812162
• Lead Sponsor: Purdue University

Brief Summary

The purpose of this study is to identify how adult men respond to a weight loss diet that includes pork and eggs and increasing the number of meals consumed throughout the day. This is a 13-week study (12-weeks of weight loss and 1-week of baseline measurement).

Detailed Description

Not available

Study Timeline

• Study Start: 2007-01
• Study First Submitted: 2008-12-18
• Study First Submitted QC: 2008-12-18
• Study First Posted: 2008-12-22
• Primary Completion: 2009-02
• Study Completion: 2011-07
• Status Verified: 2013-01
• Last Update Submitted: 2013-01-16
• Last Update Posted: 2013-01-17

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 48

Inclusion Criteria

• Age range: 21 years and older
• Body mass index between 25.0-39.9 kg/m2
• Weight stable (< 4.5 kg (~10 lbs) weight gain or loss within last 6 months)
• Body fat >25% (assessed by skinfold and plethysmography (if needed))
• Non-smoking (within the last 6 months)
• Constant habitual activity patterns (within last 3 months)
• Clinically normal blood profiles (specifically, normal liver and kidney function; fasting blood glucose <110 mg/dl)
• Not taking medications known to influence appetite or metabolism
• Non-diabetic

Exclusion Criteria

• Age: <21 years
• Body mass index: outside of the 25.0-39.9 kg/m2 range
• Gained or lost > 4.5 kg (10 lbs) within the last 6 months
• Body fat <25% as assessed by plethysmography
• Smoker (currently or within the last 6 months)
• Intermittently been involved in a diet and/or exercise program within the last 3 months
• Clinically abnormal blood profiles as identified by our study physician, Arthur Rosen, MD
• Taking medications (currently or within the last 3 months) known to influence appetite or metabolism
• Clinically diagnosed as diabetic
• Allergies to eggs
• Lactose intolerance
• Clinically diagnosed with diverticulosis
• Clinically diagnosed with diverticulitis

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
1	Energy Restriction	High protein diet.
2	Energy Restriction	Lower protein diet.

Primary Outcome Measures

Name	Time	Method
The primary aim is to examine the effects of increased protein intake on appetite, selected appetite hormones (insulin, leptin, ghrelin), whole body energy expenditure, and body composition (fat mass and fat-free mass) changes.	12 week

Secondary Outcome Measures

Name	Time	Method
The secondary aim of this study is to evaluate the effects of meal frequency on appetite by asking the men to frequently rate their appetite on days that they purposefully eat 3 vs. 6 times/day.	12 week

Trial Locations

Locations (1)

Purdue University; 🇺🇸 West Lafayette, Indiana, United States