Prognostication of Recovery in Early Disorders of Consciousness Study
- Conditions
- Disorders of Consciousness Due to Severe Brain Injury
- Registration Number
- NCT04692922
- Lead Sponsor
- Massachusetts General Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not yet recruiting
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria:<br><br> - Acute brain injury (including ischemic stroke, intracranial hemorrhage, anoxic brain<br> injury, traumatic brain injury, encephalitis)<br><br> - Inability to follow commands, speak intelligibly, or communicate (i.e., diagnosis of<br> coma, vegetative state, or minimally conscious state minus) due to the underlying<br> brain injury and within 28 days of the brain injury<br><br> - Age 18 or greater.<br><br>Exclusion Criteria:<br><br> - Subjects will be excluded if they do not speak English (given the reliance on verbal<br> questionnaires conducted in English) or if they regain the ability to follow<br> commands, speak intelligibly or communicate (i.e., improves to minimally conscious<br> state plus or greater) before they undergo MRI or EEG.
Not provided
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Glasgow Outcome Scale-Extended
- Secondary Outcome Measures
Name Time Method