Incidence of genetic abnormalities in patients with primary hypereosinophilia
- Conditions
- The patient 18 years and older ,The patients diagnosed with primary hypereosinophilia leukocyte count more than 1,500 per microliter for a period of more than 1 month.Incidence of genetic abnormalities in patients with primary hypereosinophilia.
- Registration Number
- TCTR20210514006
- Lead Sponsor
- Siriraj Hospital Mahidol University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 151
1) The patients diagnosed with primary hypereosinophilia type white blood cells greater than 1,500 per microliter for a period of more than 1 month
2) 18 years of age and over
3) Patients who received the gene test The specific targeted fusion gene panel with hypereosinophilia
4) was welcomed to join the program by signing.
1.The patient was detected from a bacterial infection by antibody detection Research projects in which patients are examined. Incidence of nasopharyngeal carcinoma in patients primary hypereosinophilias 686 / 2563 (IRB2)
2.Patients with allergic history
3.Asthma patients
4. Patients with immune diseases
5 Patients diagnosed with various cancers are not in peacetime.
6. History of steroid use in patients with herbs or drugs in the past three months
7. The patients had a history of adverse events leading to leukocyte disease, hypertension, and xa0;
Penicillin, cephalosporin, GM-CSF, NSAID, ranitidine, isopropanol, isopropanol, alanine, amazillin sulfate, chlorazine, chlorazine Cyclospora
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Mutations in hypereosinophilic patients first clinic visit Next generation sequencing for targeted gene mutations
- Secondary Outcome Measures
Name Time Method Overall survival 5 years From medical record (date of diagnosis, date of death, and date of last follow up)