The effect of a specific medication or placebo on modulating induced muscle pai
Completed
- Conditions
- Experimentally simulated tennis elbow (lateral epicondylalgia) in healthy controlsMusculoskeletal -
- Registration Number
- ACTRN12606000498594
- Lead Sponsor
- Dr Helen Slater
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Healthy controls; comprehensive musculoskeletal physical examination will be performed on both upper limbs to ensure full pain free range of elbow and wrist motion, and no abnormal tenderness to palpation of the soft tissues in the extensor muscles of the forearm and wrist (Haker 1993), or abnormally reduced muscle length.
Exclusion Criteria
Involvement of the contralateral arm, cervicothoracic spinal pathology, other upper limb musculoskeletal disorders or neurological disorders.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Quantitative sensory testing battery including: Mechanical pressure pain sensitivity in muscles[Pre and post exercise at Day 0 and pre, during and post hypertonic saline induced muscle pain at Day 1and 2.];Quantitative sensory testing battery including: Pain intensity profile (VAS, onset, duration), and referred pain areas.[During hypertonic saline induced muscle pain at Day 1and 3.];Quantitative sensory testing battery including: McGill Pain Questionnaire[Post hypertonic saline induced muscle pain at Day 1 and 4.];Quantitative sensory testing battery including: Maximal grip strength and maximal wrist extension force.[Pre and post exercise at Day 0 and at Day 1 pre, during and post hypertonic saline induced muscle pain]
- Secondary Outcome Measures
Name Time Method Muscle soreness (modified Likert scale).[Pre and post exercise at Day 0 and at Day 1 pre, during and post hypertonic saline induced muscle pain.]