induction of general anesthesia with two infusion techniques compared with standard technique

Not yet recruiting

• Conditions: PATIENTS UNDERGOING SURGERY UNDER GENERAL ANESTHESIA

• Registration Number: CTRI/2016/04/006879
• Lead Sponsor: Dean Research JIPMER

Brief Summary

our aim is to find out the dose required for induction of general anesthesia using etomidate under entropy guidance using low concentration infusion technique. by doing this we want to study whether the dose reduction achieved is associated with reduction in side effects associated with it as many are dose dependant

Detailed Description

Not available

Study Timeline

• Study Start: 2016-03-08
• Last Update Posted: 2016-04-26

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

AMERICAN PHYSICAL STATUS CLASSIFICATION 1 & 2.

Exclusion Criteria

Pregnant / Breast feeder The mentally ill Drug abuser Alcohol intoxication Patients on steroids If the infusion dose exceeds the standard bolus dose of 0.2mg/kg.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare the total dose of etomidate required	our time points are | 1) Time required for loss of eye lash reflex | 2) Time required to reach entropy value of 50
for induction with 50mcg/kg/min infusion and	our time points are | 1) Time required for loss of eye lash reflex | 2) Time required to reach entropy value of 50
25mcg/kg/min infusion with standard dose 0.2mg/kg	our time points are | 1) Time required for loss of eye lash reflex | 2) Time required to reach entropy value of 50
of Etomidate	our time points are | 1) Time required for loss of eye lash reflex | 2) Time required to reach entropy value of 50

Secondary Outcome Measures

Name	Time	Method
To assess and compare the hemodynamic	parameters in between different treatment

Trial Locations

Locations (1)

JIPMER; 🇮🇳 Pondicherry, PONDICHERRY, India

JIPMER

🇮🇳Pondicherry, PONDICHERRY, India

Dr Rajiv

Principal investigator

9566297044

G.RAJIV2008@GMAIL.COM