Glycemic Response of Cooked Grains Including Sorghum
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 10
- 主要终点
- Blood glucose
研究概览
简要总结
Given the interest in gluten-free foods and discovering dietary means to prevent metabolic disorders, this study was designed to determine the glycemic responses of four (4) grains and flours (corn, rice, wheat, and sorghum). The grain products (gruel) will be eaten by subjects and blood glucose will be collected prior to and after eating over the course of two hours. A dextrose solution, dosed to provide a like amount of available carbohydrate, will serve as the control treatment.
详细描述
Gruel was formed via a 1:9 ratio of grain (30 g) to water (270 ml) and cooked until thickened by placing water and grain mixture in a beaker and placed in a hot water bath (cooked over a stove/heating unit). The gruel was allowed to cool for 3-5 minutes before eating. The consistency of the gruel was similar to oatmeal. Subjects had a resting blood sample collected for assessment of fasting blood glucose, then ate the gruel (or control sucrose, 22g) that was assigned for that day -- they returned for the other gruel meals or sucrose control determined by Latin Square randomization. Finger stick blood samples where then collected at 30, 60, 90, and 120 minutes after eating the gruel (or sucrose) began.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Apparently healthy with no known diseases
排除标准
- •Known metabolic, cancer, cardiovascular disease/condition
研究组 & 干预措施
Wheat
Wheat flour
干预措施: Glycemic response to wheat flour (Other)
F-1000 (fontanelle flour)
Fontenel sorghum flour
干预措施: Glycemic response of F-1000 (Other)
Sumac
Sumac sorghum flour
干预措施: Glycemic response to sumac sorghum flour (Other)
MMR
MMR cultivar of sorghum flour -- from MMR Genetics, a company that produces sorghum seed.
干预措施: Glycemic response to MMR sorghum flour (Other)
Sucrose
Table sugar
干预措施: Glycemic response to sucrose (Other)
结局指标
主要结局
Blood glucose
时间窗: Before eating (time 0) and 30, 60, 90, and 120 minutes after eating to measure the change in blood glucose due to the different food.
This is an acute (over 2 hours) trial to measure blood glucose (glycemic response) to food.
次要结局
未报告次要终点
研究者
Mark D. Haub
Professor
Kansas State University
