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临床试验/NCT03254082
NCT03254082已完成不适用

Glycemic Response of Cooked Grains Including Sorghum

Kansas State University0 个研究点目标入组 10 人开始时间: 2010年9月最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
10
主要终点
Blood glucose

研究概览

简要总结

Given the interest in gluten-free foods and discovering dietary means to prevent metabolic disorders, this study was designed to determine the glycemic responses of four (4) grains and flours (corn, rice, wheat, and sorghum). The grain products (gruel) will be eaten by subjects and blood glucose will be collected prior to and after eating over the course of two hours. A dextrose solution, dosed to provide a like amount of available carbohydrate, will serve as the control treatment.

详细描述

Gruel was formed via a 1:9 ratio of grain (30 g) to water (270 ml) and cooked until thickened by placing water and grain mixture in a beaker and placed in a hot water bath (cooked over a stove/heating unit). The gruel was allowed to cool for 3-5 minutes before eating. The consistency of the gruel was similar to oatmeal. Subjects had a resting blood sample collected for assessment of fasting blood glucose, then ate the gruel (or control sucrose, 22g) that was assigned for that day -- they returned for the other gruel meals or sucrose control determined by Latin Square randomization. Finger stick blood samples where then collected at 30, 60, 90, and 120 minutes after eating the gruel (or sucrose) began.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Other
盲法
None

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Apparently healthy with no known diseases

排除标准

  • Known metabolic, cancer, cardiovascular disease/condition

研究组 & 干预措施

Wheat

Experimental

Wheat flour

干预措施: Glycemic response to wheat flour (Other)

F-1000 (fontanelle flour)

Experimental

Fontenel sorghum flour

干预措施: Glycemic response of F-1000 (Other)

Sumac

Experimental

Sumac sorghum flour

干预措施: Glycemic response to sumac sorghum flour (Other)

MMR

Experimental

MMR cultivar of sorghum flour -- from MMR Genetics, a company that produces sorghum seed.

干预措施: Glycemic response to MMR sorghum flour (Other)

Sucrose

Active Comparator

Table sugar

干预措施: Glycemic response to sucrose (Other)

结局指标

主要结局

Blood glucose

时间窗: Before eating (time 0) and 30, 60, 90, and 120 minutes after eating to measure the change in blood glucose due to the different food.

This is an acute (over 2 hours) trial to measure blood glucose (glycemic response) to food.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Mark D. Haub

Professor

Kansas State University

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