Peripheral and Central Nervous System Contributions to the Subjective Experience of Emotions

Completed

• Conditions: Panic attack; 10002861; anxiety attacks

• Registration Number: NL-OMON49383
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 9 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 64

Inclusion Criteria

18-55 years old, healthy subject, adequate sensitivity to CO2 (as tested in the
screening)

Exclusion Criteria

mental or physical disorder/illness, pregnant, relatives with panic disorder

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Main study parameters are changes (from pre- to immediately post- CO2<br /><br>inhalation) per condition (atenolol, metoprolol, placebo) in fear, discomfort<br /><br>and panic symptom ratings, as measured by questionnaires. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary outcomes are changes in physiological parameters (e.g., skin<br /><br>conductance, heart rate).</p><br>