Inflammatory injury of the lung after cardiac surgery

Completed

• Conditions: Acute Lung Injury; Inflammatory induced pulmonary Injury; 10019280; 10038716; 10007593

• Registration Number: NL-OMON41450
• Lead Sponsor: eids Universitair Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2018-01-01
• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 120

Inclusion Criteria

Adult patients scheduled for cardiac surgery

Exclusion Criteria

minor
ermergency surgery
not able to sign informed consent

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Length of ICU-stay, length of hospital-stay, ICU-mortality, 30-day mortality</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>1. Prognostic: occurrence of ALI and ARDS, duration of mechanical ventilation,<br /><br>need for renal replacement therapy<br /><br>2. Etiologic: levels and time course of markers of inflammation and<br /><br>ischemia-reperfusion in relation to the clinical course (such as AlI and ARDS,<br /><br>duration of mechanical ventilation, need for renal replacement therapy,<br /><br>ICU-stay, hospital-stay, ICU-mortality, 30-day mortality) particular in<br /><br>patients following complex heart surgery as opposed to low risk surgery<br /><br>3. Methodologic: Investigate the value of collecting minimal invasive<br /><br>endobronchial samples in cardiac surgery patients.</p><br>