Comparing the efficacy of Locally Delivered Aloe Vera against Fusobacterium nucleatum after Scaling and Root planing in Chronic Periodontitis patients - A Randomized controlled trial.
Phase 2
Completed
- Conditions
- Health Condition 1: K053- Chronic periodontitis
- Registration Number
- CTRI/2022/08/044625
- Lead Sponsor
- Prem Kumar
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 35
Inclusion Criteria
Healthy Subjects (Without any Systemic Diseases)
with Bilaterally comparable periodontal defetcs.
Pocket depth : 5-7mm
Clinical attachment loss : More than 3mm
Exclusion Criteria
History of periodontal or antibiotic therapy in past 6 months.
Any known disease or intake of any medication that affects periodontal status.
Teeth with poor periodontal prognosis.
Allergic to herbal medications.
Aggressive periodontitis.
Current Smokers and Alcoholics.
Pregnant or Lactating females.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Primary outcome:To check the levels of subgingival Fusobacterium nucleatum at baseline and after 3 months of treatment. <br/ ><br> <br/ ><br>Sample Collection method:Subgingival Plaque samples will be collected before treatment and after 3 months of treatment using 30s sterile paper points and immediately transferred to buffer solution and stored in -80 degree celcius.Timepoint: At baseline and after 3 months of treatment (12weeks)
- Secondary Outcome Measures
Name Time Method To evaluate the following clinical parameters at baseline and after 3 months of treatment: <br/ ><br> <br/ ><br>1.Probing Pocket Depth(PPD) <br/ ><br>2.Clinical Attachment Level(CAL) <br/ ><br>3.Gingival Bleeding Index (GBI) <br/ ><br>4.Plaque Index (PI)Timepoint: At baseline and after 3 months of treatment(12 weeks)