A clinical trial to compare two drugs bupivacaine and ropivacaine in TAP block for pain relief after completion of surgery in patients undergoing caesarean section

Not yet recruiting

• Conditions: Sequelae of complication of pregnancy, childbirth, and the puerperium,

• Registration Number: CTRI/2021/09/036392
• Lead Sponsor: Dr Hetal N Kanabar

Brief Summary

This study is a randomized ,double blind ,parellel group, controlled trial comparing the safety and efficacy of bupivacaine 0.25%  and ropivacaine 0.5% in transeversus abdominis plane block in 50 patients undergoing lower segment caesarean section ,will be conducted at GMERS Medical College, Junagadh. The primary outcome measures will be duration of analgesia that is from the time of giving TAP block to time of giving first rescue analgesic (when VAS Score more than or equal to 6 ). Secondary outcomes will be any local site infection or haematoma, any secondary complications of local anaesthetic agents such as cardiotoxicity or neurotoxicity.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2021-08-09
• Study Start: 2021-09-15

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: Female
• Target Recruitment: 50

Inclusion Criteria

ASA physical status 1 or 2, patients giving valid consent, undergoing elective lower segment caesarean section under spinal anaesthesia.

Exclusion Criteria

Known allergy to local anaesthetic agents, patients who are receiving any non-steroidal antiinflammatory drugs or opioids 48 hours prior to surgery, patients with any contraindication to spinal anaesthesia, thrombocytopenia, patients requiring general anaesthesia, local infection at the site of injection.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
First dose of rescue analgesic will be given when VAS Score more than or equal to 6	Upto 36 hours after giving TAP block

Secondary Outcome Measures

Name	Time	Method
Local site infection or haematoma, any secondary complications of local anaesthetic agents such as cardiotoxicity or neurotoxicity	Upto 36 hours after giving TAP block

Trial Locations

Locations (1)

GMERS medical college and hospital , junagadh; 🇮🇳 Junagadh, GUJARAT, India

GMERS medical college and hospital , junagadh

🇮🇳Junagadh, GUJARAT, India

Dr Hetal Kanabar

Principal investigator

9909960401

kanabarhetal@yahoo.com