COVID-19 Vaccine Messaging, Part 1

Not Applicable

Completed

• Conditions: COVID-19; Vaccination

• Registration Number: NCT04460703
• Lead Sponsor: Yale University

Brief Summary

This study tests different messages about vaccinating against COVID-19 once the vaccine becomes available. Participants are randomized to 1 of 12 arms, with one control arm and one baseline arm. We will compare the reported willingness to get a COVID-19 vaccine at 3 and 6 months of it becoming available between the 10 intervention arms to the 2 control arms.

Study participants are recruited online by Lucid, which matches census based sampling in online recruitment.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2020-07-02
• Study Start: 2020-07-03
• Study First Submitted QC: 2020-07-06
• Study First Posted: 2020-07-07
• Primary Completion: 2020-07-08
• Study Completion: 2020-07-08
• Status Verified: 2022-04
• Last Update Submitted: 2022-04-29
• Last Update Posted: 2022-05-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 4000

Inclusion Criteria

• At least 18 years of age
• US resident

Exclusion Criteria

• Younger than 18 years of age
• Non-US resident
• Do not consent

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Intention to get COVID-19 vaccine	Immediately after intervention, in the same survey in which the intervention message is provided	This is a self reported measure, immediately after the intervention message, of the likelihood of getting a COVID-19 vaccination within 3 months and then 6 months of it becoming available. During analysis, responses among those assigned to different intervention messages will be compared to those in the control group.

Secondary Outcome Measures

Name	Time	Method
Persuade others item	Immediately after intervention, in the same survey in which the intervention message is provided	This is a measure of a willingness to persuade others to take the COVID-19 vaccine.
Fear of those who have not been vaccinated	Immediately after intervention, in the same survey in which the intervention message is provided	This is a measure of a comfort with an unvaccinated individual visiting an elderly friend after a vaccine becomes available
Vaccine confidence scale	Immediately after intervention, in the same survey in which the intervention message is provided	This is a validated scale. This scale will be used to assess the impact of the messages on vaccine confidence. (Outcome assessed only for the half of the sample that answers these items post-treatment)
Social judgment of those who do not vaccinate	Immediately after intervention, in the same survey in which the intervention message is provided	This is a scale composed of 4 items measuring the trustworthiness, selfishness, likeableness, and competence of those who choose not to get vaccinated after a vaccine becomes available

Trial Locations

Locations (1)

Yale University; 🇺🇸 New Haven, Connecticut, United States