Effects of a lactic acid bacteria beverage on bowel movement and intestinal microflora: double blind, placebo-controlled study
- Conditions
- Subjects with a tendency for constipation
- Registration Number
- JPRN-UMIN000015338
- Lead Sponsor
- TTC Co., Ltd.
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 60
Not provided
(1) Subjects regularly using drugs (constipation drugs, intestinal drugs, etc.) , health foods (senna tea, kefir, etc.), or foods for specified health use (indigestible dextrin, chitosan, oligosaccharides, etc.) (2) Subjects having a large amount of foods such as lactic acid bacteria beverage, food containing lactic acid bacteria (yogurt, kimchi, pickles, sushi fermented with fish and vegetables, etc.), lactic acid bacteria preparation, dietary fiber enriched food, and oligosaccharides more than three times a week (3) Subjects visiting the hospital for diseases related bowel movements and using drugs, or using commercial laxative (4) Subjects currently undergoing treatment with digestive diseases that affect the study or having a surgical history of digestive system (except appendicectomy) (5) Subjects having diseases (irritable enteritis, ulcerative colitis, etc.) affecting bowel movement or a history of these diseases (6) Subjects who are judged as unsuitable for the study based on the results of lifestyle questionnaire (7) Subjects judged as unsuitable for this study based on the results of clinical examination or cardiopulmonary abnormality (8) Subjects having possibilities for emerging allergy related to the study (9) Subjects having a disease requiring regular medication or a history of serious diseases for which medication was required (10) Subjects who have participated in other clinical studies (11) Subjects who intend to become pregnant or lactating (12) Subjects judged as unsuitable for the study by physician for other reasons
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Defecation frequency, defecation days, intestinal microflora
- Secondary Outcome Measures
Name Time Method Stool output, fecal condition, quantitative analysis of intestinal microflora (total anaerobes, Bifidobacterium, Clostridium perfringens), fecal water content, fecal pH