PET-CT Imaging Findings and Metabolic Parameters in Elderly Patients With Lymphoma
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 63
- 主要终点
- FDG-PET/CT Imaging Pattern Description in Elderly Lymphoma Patients
研究概览
简要总结
This study investigates PET-CT imaging patterns and metabolic parameters in elderly patients (≥60 years) diagnosed with lymphoma, aiming to enhance diagnostic accuracy and prognosis using 18F-FDG PET/CT scans.
详细描述
This cross-sectional study involves both retrospective and prospective data collection from elderly lymphoma patients (aged 60 years or older) at the Nuclear Medicine Unit, South Egypt Cancer Institute. It evaluates the PET-CT imaging findings alongside metabolic parameters such as Standardized Uptake Value (SUV), Metabolic Tumor Volume (MTV), and Total Lesion Glycolysis (TLG). The study addresses diagnostic challenges in elderly patients due to atypical presentations and comorbidities and fills the gap of scarce local data in Egypt. Imaging analysis includes visual and semiquantitative assessment of lymphatic and extranodal lesions post-injection of 18F-FDG, assessing tumor metabolic activity to provide prognostic insights. Data analysis uses SPSS with relevant statistical tests to validate findings.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 60 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •- Age ≥ 60 years
- •Histopathological diagnosis of lymphoma
排除标准
- •- Presence of other concurrent active malignancies
- •Uncontrolled diabetes mellitus with blood glucose > 200 mg/dL at the time of PET/CT scan
结局指标
主要结局
FDG-PET/CT Imaging Pattern Description in Elderly Lymphoma Patients
时间窗: At time of initial PET/CT scan performed as part of routine clinical evaluation
The main outcome is the characterization of metabolic and anatomical findings from 18F-FDG PET/CT scans among elderly patients (≥60 years) diagnosed with lymphoma. This includes describing the visual appearance, extent, and distribution of disease lesions observed on initial imaging.
次要结局
未报告次要终点
研究者
Marwa Mamdouh Ekram
Resident at Nuclear Medicine unit, Radiotherapy and Nuclear Medicine Department, South Egypt Cancer Institute
Assiut University