DRKS00033075RecruitingNot Applicable
Investigation of cerebrovascular reactivity in post-COVID-19 syndrome using functional magnetic resonance imaging
niversitätsklinikum Tübingen0 sites90 target enrollmentStarted: December 4, 2023Last updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Recruiting
- Sponsor
- Enrollment
- 90
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Observational
Eligibility Criteria
- Ages
- 18 Years to 50 Years (—)
- Sex
- All
Inclusion Criteria
- •Willingness to provide the written informed consent and the ability to give consent.
- •-SARS-CoV-2 infection confirmed by PCR test at least 12 weeks ago and the presence of a clinical neurological post-COVID syndrome (depending on the subgroup, leading symptom complex fatigue/concentration and memory disorder/headache/dizziness or leading symptom complex myopathy/neuropathy).
- •-Inclusion criterion for the control group after SARS-CoV-2 infection without post-COVID syndrome is a SARS-CoV-2 infection at least 12 weeks ago, confirmed by PCR test.
Exclusion Criteria
- •-Contraindications against MRI examinations; if metallic foreign bodies are present, it is checked before the examination whether the materials used are MRI-compatible and the examination can take place without increased risk
- •- Persons with known ischemic infarcts, as well as known hemodynamically relevant extra- and intracranial and vascular diseases
- •- Persons with known neurological or psychiatric illnesses prior to infection with SARS-CoV-2
- •- Persons with illnesses that prevent them from lying quietly in the examination device for 60 minutes (e.g. pain, claustrophobia, limited temperature sensitivity and/or increased sensitivity to body heating)
- •- Persons who do not appear to be cognitively or cardiopulmonarily capable of taking short breaths lasting 9 seconds
- •- Persons whose pregnancy has not been ruled out with certainty
- •- In the subgroup consisting of persons without post-COVID syndrome any of the following symptoms:
- •o Muscle weakness/muscle pain
- •o Anxiety/depression
- •o Memory/concentration disorders
- •o Smell/taste disorders
- •o Sleep disorders
- •o Dizziness
Investigators
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