Maxillary Canine Retraction Assisted With Micro-osteoperforations Versus Injectable Platelet Rich Fibrin

Phase 2

• Conditions: Effects of; Movement of Teeth Assiste Wit MOPS and I-prf
• Interventions: Combination Product: injectable platelet rich fibrin versus microosteoperforation

• Registration Number: NCT05960825
• Lead Sponsor: Al-Azhar University

Brief Summary

The present clinical comparative study will be undertaken for assessment of two different modalities of maxillary canine retraction assisted with microosteoperforations versus injectable platelet rich fibrin.

Detailed Description

Group I: will include 9 patients who willreceive MOPs with maxillary canine retraction that will be performed on intervention sides according to a standardized protocol.

▪ Group II: will include 9 patients receive i-PRF that will be performed on intervention sides according to a standardized protocol.

Study Timeline

• Status Verified: 2023-07
• Study First Submitted: 2023-07-15
• Study First Submitted QC: 2023-07-22
• Last Update Submitted: 2023-07-22
• Study First Posted: 2023-07-27
• Last Update Posted: 2023-07-27
• Study Start: 2023-12
• Primary Completion: 2024-03
• Study Completion: 2024-08

Recruitment & Eligibility

• Status: ENROLLING_BY_INVITATION
• Sex: All
• Target Recruitment: 18

Inclusion Criteria

1. An age ranges from 15-22 years.
2. Severe crowding or protrusion requiring 1st premolars extractions followed by symmetrical canine retraction.
3. All permanent teeth present, 3rd molars are excluded.
4. Good oral and general health.
5. No systemic disease/medication that could interfere with OTM.
6. No previous orthodontic treatment.

Exclusion Criteria

1. Patient diagnosed to have an indication for non-extraction approach.
2. Poor oral hygiene or periodontally compromised patient.
3. Patient with craniofacial anomalies or previous history of trauma, bruxism or parafunctions.
4. Previous orthodontic treatment.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: FACTORIAL

Arm && Interventions

Group	Intervention	Description
Group MOPs	injectable platelet rich fibrin versus microosteoperforation	Group MOPs : will include 9 patients who willreceive MOPs with maxillary canine retraction that will be performed on intervention sides according to a standardized protocol.
Group i-PRF	injectable platelet rich fibrin versus microosteoperforation	group i-PRF: will include 9 patients receive i-PRF that will be performed on intervention sides according to a standardized protocol

Primary Outcome Measures

Name	Time	Method
Direct clinical assessment of the amount of maxillary canine retraction i.e. amount of extraction space closure before and after four months observation period and on every 28 days observation period according to standardized method	4months	Direct clinical assessment of the amount of maxillary canine retraction i.e. amount of extraction space closure before and after four months observation and every 28 days period and on every 28 days observation period according to standardized method. 2. Study cast assessment: • The amount of maxillary canine retraction on both sides will be measured immediately before starting canine retraction and at each observation interval by using a software for the scanned models according to standardized method

Trial Locations

Locations (1)

AlAzhar university; 🇪🇬 Cairo, Egypt