A Clinical Study of Acne Scars and Split-face comparative study of Fractional CO2 Laser vs Fractional CO2 Lazer with Platelet-rich Plasma Theray in Treatment of Atrophic Acne Scars
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 188
- 试验地点
- 1
- 主要终点
- We will be able to clinically grade acne scars for the purpose of finding best possible treatment modality for treatment of atrophic acne scars
研究概览
简要总结
Aim: Toclinically evaluate and grade acne scars, and to compare efficacy and safety of fractionalco2 laser versus fractional co2 laser with platelet rich plasma therapy in the treatmentof atrophic acne scars.
Primaryobjective: To determine the frequency of various types and grading of acne scars.
Secondaryobjective: To evaluate the efficacy and safety of fractional co2 laserversus fractional co2 laser withplatelet rich plasma therapy in the treatment of atrophic acne scars.
Rationale for the study: Grading and classifying acne scars will assess theseverity and prioritizes the choice of treatment. Manytreatment options are available for atrophic acne scars, but still, it ischallenging to manage as the condition can be refractive. Gold standardtreatment modality for atrophic acne scars are ablative lasers. Platelet richplasma therapy is a newer treatment modality used for atrophic acne scars,which may have additional benefits compared to laser therapy alone. Thisstudy intends to compare the efficacy and safety of fractional co2 laser andplatelet rich plasma therapy, for the treatment of atrophic acne scars.
研究设计
- 研究类型
- Interventional
- 分配方式
- Not Applicable
- 盲法
- Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 45.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients with acne scar for clinical study Patients with grade 3and 4 acne scars for interventional study.
排除标准
- •Patients with HIV, HBV, Reccurent HSV.
- •Patients with bleeding manifestations.
- •Patients with keloidal tendencies.
- •Patients with unrealistic expectations and not willing for follow-up.
结局指标
主要结局
We will be able to clinically grade acne scars for the purpose of finding best possible treatment modality for treatment of atrophic acne scars
时间窗: 1- Baseline
次要结局
- We will be able to compare the efficacy and safety of Fractional CO2 Laser Therapy with Platelet-rich Plasma Therapy versus Fractional CO2 Laser Therapy alone in treatment of atrophic acne scars.(2- 4th week,)