Study of acne scars and research on best treatment modality for depressed acne scars

Recruiting

• Conditions: Acne vulgaris, (2) ICD-10 Condition: O||Medical and Surgical,

• Registration Number: CTRI/2023/03/050273
• Lead Sponsor: Yenepoya Medical College Hospital

Brief Summary

Aim: Toclinically evaluate and grade acne scars, and to compare efficacy and safety of fractionalco2 laser versus fractional co2 laser with platelet rich plasma therapy in the treatmentof atrophic acne scars.

Primaryobjective: To determine the frequency of various types and grading of acne scars.

Secondaryobjective: To evaluate the efficacy and safety of fractional co2 laserversus       fractional co2 laser withplatelet rich plasma therapy in the treatment of atrophic acne scars.

Rationale for the study: Grading and classifying acne scars will assess theseverity and prioritizes the choice of treatment. Manytreatment options are available for atrophic acne scars, but still, it ischallenging to manage as the condition can be refractive. Gold standardtreatment modality for atrophic acne scars are ablative lasers. Platelet richplasma therapy is a newer treatment modality used for atrophic acne scars,which may have additional benefits compared to laser therapy alone. Thisstudy intends to compare the efficacy and safety of fractional co2 laser andplatelet rich plasma therapy, for the treatment of atrophic acne scars.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2023-02-03
• Study Start: 2023-03-15

Recruitment & Eligibility

• Status: Open to Recruitment
• Sex: All
• Target Recruitment: 188

Inclusion Criteria

Patients with acne scar for clinical study Patients with grade 3and 4 acne scars for interventional study.

Exclusion Criteria

• Patients with HIV, HBV, Reccurent HSV.
• Patients with bleeding manifestations.
• Patients with keloidal tendencies.
• Patients with unrealistic expectations and not willing for follow-up.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
We will be able to clinically grade acne scars for the purpose of finding best possible treatment modality for treatment of atrophic acne scars	1- Baseline

Secondary Outcome Measures

Name	Time	Method
We will be able to compare the efficacy and safety of Fractional CO2 Laser Therapy with Platelet-rich Plasma Therapy versus Fractional CO2 Laser Therapy alone in treatment of atrophic acne scars.	2- 4th week,

Trial Locations

Locations (1)

Yenepoya Medical College Hospital; 🇮🇳 Kannada, KARNATAKA, India

Yenepoya Medical College Hospital

🇮🇳Kannada, KARNATAKA, India

Sebastian Thomas

Principal investigator

8547145988

sebastianthomas1994@gmail.com