Advanced Glycation End Products in Patients with Peripheral Arterial Occlusive Disease or Abdominal Aortic Aneurysm
- Conditions
- Patients with an abdominal aortic aneurysm (AAA) or peripheral arterial occlusive disease (PAOD) with and without diabetes mellitus.
- Registration Number
- NL-OMON29072
- Lead Sponsor
- niversity Medical Center Groningen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 120
Inclusion Criteria
Age > 18 years old.
AAA or PAOD
Exclusion Criteria
Both AAA and PAOD
Inflammatory disease (rheumatoid artritis, SLE, giant cell artritis, Takayasu disease)
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Advanced glycation end products in the arterial wall
- Secondary Outcome Measures
Name Time Method Serum, urine and skin AGEs (measured by SAF).<br /><br>Mechanical properties of the arterial wall.<br /><br>Serum, urine and tissue markers of inflammation and oxidative stress