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Perampanel as adjunctive therapy in drug resistant epilepsy in adolescents and children waiting for epilepsy surgery: a multicenter observational study in Thailand

Completed
Conditions
The patients with the age between 1 month and 18 years treated with PER and diagnosed with DRE and in the waiting list for epilepsy surgery
Perampanel
anti-seizure medication
drug-resistant
treatment-resistant epilepsy
Registration Number
TCTR20220322006
Lead Sponsor
Phramongkutklao Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
85
Inclusion Criteria

1. patients with the age between 1 month and 18 years treated with PER, 2. having complete records of baseline seizure frequency for at least 3 months prior to starting PER, 3. taking PER for at least 6 months, 4. diagnosed with DRE and in the waiting list for epilepsy surgery.

Exclusion Criteria

1. patients with generalized epilepsy, 2. patients with epilepsy syndrome.

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
seizure reduction 180 days extract from the medical record
Secondary Outcome Measures
NameTimeMethod
adverse effect, ataxia, mood disturbamce 180 days extract from the medical record
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