The effect of isoflavone supplement intake on gene-expression in postmenopausal wome
Completed
- Conditions
- geen specifieke aandoening, door het gebruik van micro-arraysnvt
- Registration Number
- NL-OMON34551
- Lead Sponsor
- Wageningen Universiteit
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 36
Inclusion Criteria
women
45-70 year
post-menopausal
equol-producing
Exclusion Criteria
current use of contraceptives containing hormones
current use of hormone replacement therapy
current soy product use (more than once a week)
current isoflavone supplement use (more than once a week)
current use of medication containing sexhormones or sexhormone-triggering compounds
current use of anti-inflammatory drugs
use of antibiotics in the past 6 months
severe heart disease
thyroid disorders
complete ovarectomy
thyroidectomy
prior diagnosis of cancer in medical history
Alcohol and drug abuse
Current smoking habits
BMI >35 kg/m2
allergic to soy (products)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The main study parameter is gene-expression measured by micro-arrays. </p><br>
- Secondary Outcome Measures
Name Time Method <p>Isoflavone levels in plasma and in spoturine</p><br>