Dehydroepiandrosterone Supplementation for Poor Responder Patients During in Vitro Fertilization Treatment

Not Applicable

Completed

• Conditions: Ovarian Stimulation
• Interventions: Drug: dehydroepiandrosterone crystalline fine powder

• Registration Number: NCT01145144
• Lead Sponsor: Meir Medical Center

Brief Summary

The aim of this study was to evaluate the effect of dehydroepiandrosterone supplementation on in vitro fertilization performance and outcome among poor-responder patient.

Detailed Description

Not available

Study Timeline

• Study Start: 2008-01
• Primary Completion: 2009-07
• Study Completion: 2009-07
• Study First Submitted: 2010-05-03
• Status Verified: 2010-06
• Study First Submitted QC: 2010-06-15
• Last Update Submitted: 2010-06-15
• Study First Posted: 2010-06-16
• Last Update Posted: 2010-06-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: Not specified

Inclusion Criteria

• previous poor response to ovarian stimulation in IVF.

Exclusion Criteria

• patients over the age of 42
• patients who received DHEA at any time.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
DHEA supplementation	dehydroepiandrosterone crystalline fine powder	DHEA was added to induction of ovulation by recombinant FSH and recombinant LH, in IVF long protocol

Primary Outcome Measures

Name	Time	Method
number of embryos reserved for transfer.
peak estradiol level.
number of retrieved oocytes.
Embryos that were graded as a top quality (according to the number of cells and percent of fragmentation)

Secondary Outcome Measures

Name	Time	Method
pregnancy rate.
live birth rate.

Trial Locations

Locations (2)

Meir Medical center IVF unit; 🇮🇱 kfar Saba, Israel

Meir Medical Center; 🇮🇱 Kfar Sava, Israel