Hair cortisol level in children with and without asthma

Completed

• Conditions: adrenal function; hypothalamic-pituitary-adrenal axis; 10001353

• Registration Number: NL-OMON38679
• Lead Sponsor: Medisch Centrum Leeuwarden

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 20

Inclusion Criteria

Healthy children: prepubertal (6-12 years), no use of steroids or medication with a potential effect on steroidmetabolism;Children with asthma: prepubertal (6-12 years), stable asthma (no additional use of medication in previous three months, no use of systemic steroids in previous three months, normal lungfunction (FEV1 >90% of predicted value)

Exclusion Criteria

Informed consent not obtained
If the child and/or parents refuses to participate or cooperate during the study

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Cortisol levels in hair samples</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Correlation between salivary cortisol levels and cortisol levels in hair samples<br /><br><br /><br>Association between cortisol levels (in saliva and hair) and symptomscore and<br /><br>lungfunction</p><br>