Salivary cortisol in children with asthma and/or rhinitis: effect of topical steroids and correlation with symptoms and lungfunctio
Completed
- Conditions
- adrenal functioncortisol level10001353
- Registration Number
- NL-OMON34524
- Lead Sponsor
- Medisch Centrum Leeuwarden
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 40
Inclusion Criteria
children 6-18 years
newly referred children who are diagnosed with asthma and/or rhinitis and who are not already using topical steroids
children with stable asthma and/or rhinitis in whom topical steroids can be tapered down to zero according to international guidelines
Exclusion Criteria
informed consent is not obtained
if a child is unwilling to participate during the study
a chronic medical condition other than asthma and/or rhinitis
use of oral steroids in the past 3 months
use of concurrent medication which may potentially affect steroidmetabolism
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>difference in salivary cortisol level before and during or after treatment with<br /><br>topical steroids</p><br>
- Secondary Outcome Measures
Name Time Method <p>correlation of salivary cortisol, symptoms of asthma, and lungfunction</p><br>