"Hemodynamic Changes During Endovascular Revascularization for Acute Stroke. An Observational Study".

• Conditions: Ischemic Stroke
• Interventions: Device: MOSTCAREup Monitoring; Device: Ecocardiography

• Registration Number: NCT04771468
• Lead Sponsor: Humanitas Clinical and Research Center

Brief Summary

Neurocardiology is an emerging specialty that addresses the interaction between the brain and the heart, i.e. the effects of cardiac injury on the brain, and the effects of brain injury on the heart. Accumulating clinical and experimental evidence suggests a causal relationship between brain damage and heart dysfunction.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2021-01-06
• Study First Submitted QC: 2021-02-23
• Study First Posted: 2021-02-25
• Status Verified: 2021-09
• Last Update Submitted: 2021-09-01
• Last Update Posted: 2021-09-02
• Study Start: 2021-10-01
• Primary Completion: 2022-06-01
• Study Completion: 2022-12-31

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Sovratentorial ischemic stroke	MOSTCAREup Monitoring	-
Sovratentorial ischemic stroke	Ecocardiography	-

Primary Outcome Measures

Name	Time	Method
Cardiac output measurement	Up to 6 hours after clot removal	Changes of cardiac output of the enrolled patients before and after clot removal.
Arterial elastance measurement	Up to 6 hours after clot removal	Changes of arterial elastance of the enrolled patients before and after clot removal.
Arterial blood pressure measurement	Up to 6 hours after clot removal	Changes of arterial blood pressure of the enrolled patients before and after clot removal.
Heart rate variability measurement	Up to 6 hours after clot removal	Changes of heart rate variability of the enrolled patients before and after clot removal.

Secondary Outcome Measures

Name	Time	Method
Transthoracic echocardiography	at the admission	Ejection Fraction measurement
Transthoracic Echocardiography	up to 3 weeks after clot removal	wave e' assessment

Trial Locations

Locations (1)

Humanitas Research Hospital; 🇮🇹 Rozzano, Milano, Italy