Circulating tumour cells in bladder cancer patients treated with chemotherapy and radical cystectomy – enumeration, characterization and evaluation of prognostic value (the CIRCH-study)

Not Applicable

Completed

• Conditions: rothelial carcinoma; Cancer

• Registration Number: ISRCTN72499664
• Lead Sponsor: und University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-05-18
• Study Completion: 2019-12-30
• Last Update Posted: 1 February 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 182

Inclusion Criteria

Locally advanced high grade urothelial carcinoma of the bladder scheduled for chemotherapy in the following settings; neoadjuvant, induction or palliative

Exclusion Criteria

Other malignant diseases

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<br> Dynamic change in CTC during chemotherapy, using the Cellsearch method<br>

Secondary Outcome Measures

Name	Time	Method
<br> 1. Progression Free Survival (PFS) from date of chemotherapy start to progression/death (via patient chart review, using clinical and radiological (RESIST 1.1) criteria.)<br> 2. Overall Survival (OS), measured as death from any cause<br>