An online testing approach to assess cognitive problems associated with cancer and cancer treatment.

Conditions: cognitive deficits
memory
planning and attention problems
10009841

Registration Number: NL-OMON35221

Lead Sponsor: Antoni van Leeuwenhoek Ziekenhuis

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Pending

Sex: Not specified

Target Recruitment: 715

Inclusion Criteria

Disease free cancer patients (equal gender distribution, age-range: 18-74) treated at the NKI-AVL with chemotherapy and/or hormonal therapy will be included.
Healthy partners (partner, family member or friend of the opposite sex with comparable age and education level) of patients will serve as control group to gather reference data.
Patients and heatlhy controls should have sufficient proficiency in Dutch language.

Exclusion Criteria

Cancer patients: involvement of the central nervous system
Healthy controls: cancer, any neurological or psychiatric symptoms which can influence cognitive performance

Study & Design

Study Type: Observational non invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>A subset of the participating patients (n=220) completes the following<br /><br>traditional neuropsychological tests:<br /><br><br /><br>1) Visual reaction time (FePsy); 2) WAIS III Digit Span (forward & backward);<br /><br>3) Corsi Block-tapping Test; 4) Trailmaking A and B (TMT); 5) Tower of London<br /><br>(TOL); 6) Controlled Oral Word Association (COWA); 7) Rey Auditory Verbal<br /><br>Learning test, short form; 8) Grooved Pegboard; 9) Japanese and caucasian brief<br /><br>affect recognition test (JACBART).<br /><br><br /><br>Also, the newly developed neuropsychological test battery is conducted by all<br /><br>patients (n=385) and healthy controls (n=330). This test consists of several<br /><br>subtests based on the here above mentioned traditional tests.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>- questionnaire on anxiety and depression: Hopkins Symptom Checklist-25<br /><br>- demographics<br /><br>- short questionnaire on internet usage</p><br>