Prone Position for Non-intubated Patients With Acute Respiratory Failure

Not Applicable

• Conditions: Respiratory Failure
• Interventions: Other: Prone position

• Registration Number: NCT00526981
• Lead Sponsor: Karolinska University Hospital

Brief Summary

The study will test the hypothesis that the prone position can be used to reduce the need for intubation and mechanical ventilation in patients with acute respiratory failure.

Detailed Description

Not available

Study Timeline

• Study Start: 2007-09
• Study First Submitted: 2007-09-06
• Study First Submitted QC: 2007-09-06
• Study First Posted: 2007-09-10
• Status Verified: 2011-09
• Last Update Submitted: 2011-09-19
• Last Update Posted: 2011-09-20
• Primary Completion: 2011-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

• bilateral pulmonary infiltrates or unilateral infiltrates involving more than one lobe on CXR
• PaO2/FIO2 < 40 kPa
• RR > 25, or attending intensivist considering likelihood of intubation > 50%

Exclusion Criteria

• unsuited for the prone position
• fulfilled inclusion criteria for more than 5 days (120 h)
• immunosuppression
• chronic lung disease
• decision of withdrawal or limitation of therapy
• pulmonary infiltrates of cardiac origin
• decreased GCS level
• PaCO2 > 10
• attending intensivist considering the patient unsuited for the prone position
• BMI > 33

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Treatment	Prone position	Prone position + all conventional treatment.

Primary Outcome Measures

Name	Time	Method
Need for intubation and mechanical ventilation	Duration of hospital stay

Trial Locations

Locations (1)

Karolinska University Hospital Solna; 🇸🇪 Stockholm, Sweden