Effect of Vitamin C on blood cortisol after Anesthesia with etomidate
Not Applicable
- Conditions
- laparotomy.Disease of intestine, unspecified
- Registration Number
- IRCT201511252804N10
- Lead Sponsor
- Deputy of Research, Shahid Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
ASA class I,II; age between 25 to 70 years old; elective laparotomy;
Exclusion criteria: severe disabling illness; Addison or Cushing disease; septic shock; severe sepsis; trauma; history of corticosteroid intake at a dose that could suppress cortico-pituitary-adrenal; duration of surgery longer than 4 hours; extreme changes in hemodynamics during surgery
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Free cortisol level. Timepoint: one sample 5 minutes before induction and another sample 4 hours after induction. Method of measurement: serum level of cortisol.;ACTH: Adrenocorticotropic hormone. Timepoint: one sample 5 minutes before induction and another sample 4 hours after induction. Method of measurement: serum level of ACTH (Adrenocorticotropic hormone).
- Secondary Outcome Measures
Name Time Method Body mass index: BMI. Timepoint: at the start of study entry. Method of measurement: clinical files of the patients.