Effect of drug on extubation response given through nebulization preoperatively
Phase 4
- Conditions
- Health Condition 1: - Health Condition 2: O- Medical and Surgical
- Registration Number
- CTRI/2024/04/066136
- Lead Sponsor
- Pondicherry Institute of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Patients between age groups 18 to 65 years and belonging to American society of Anesthesiologist physical status classification ASA-PS-I &II.
2. Patient scheduled for elective general anaesthesia procedures.
Exclusion Criteria
allergic to local anaesthetics
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the incidence and severity of cough between preoperative 0.5% Ropivacaine nebulization versus 0.9% normal saline nebulization in patients undergoing general anaesthesia with endotracheal intubation.Timepoint: Heart rate, Mean arterial pressure, spo2 will be recorded at baseline, upon tracheal intubation, every 1 minute till 5 minutes, Every 5 minutes after intubation till 20 mins, upon anaesthetic withdrawal, upon eye opening on verbal commands, upon tracheal extubation, immediately after extubation, every 5 minutes after extubation till 20 minutes. <br/ ><br>Incidence and severity of cough by Modified 4 point Minogue scale.
- Secondary Outcome Measures
Name Time Method To compare perioperative hemodynamics, time to extubation, incidence and severity of sore throatTimepoint: Hemodynamics will be recorded at baseline,upon tracheal intubation,every 1 minute till 5 minutes,Every 5 minutes after intubation till 20 mins, upon anaesthetic withdrawal,upon eye opening on verbal commands, upon tracheal extubation every 5 minutes after extubation till 20 minutes. <br/ ><br>Sore throat recorded at 0,2,4,6 and 24 hrs.