CoKnie
Recruiting
- Conditions
- Osteoarthritis patients in who total knee replacement is planned
- Registration Number
- NL-OMON27720
- Lead Sponsor
- Wageningen University & Research
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 92
Inclusion Criteria
Planned for total knee replacement therapy
> 18 years old and mentally competent
Exclusion Criteria
Current use (latest use one week or less before inclusion) of supplements (like glucosamine, chondroitin, green-lipped mussel, curcumin or blackcurrant leaf).
Diagnosed with Rheumatoid Arthritis
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary objective is to investigate the difference between the two groups in change from baseline in Oxford Knee Scores at 6 weeks after the surgery.
- Secondary Outcome Measures
Name Time Method Secondary objectives are to assess the difference between the two groups <br>in change from baseline in Oxford Knee Scores at 12 weeks after the surgery and at 6 months after the surgery.<br /><br>On pain VAS scores measured at hospital admission, 2 weeks post-surgery, and 6 weeks post-surgery.<br /><br>On the amount and period of pain relieving therapies, <br>On inflammation in synovial fluid, muscle and knee function, functional tests and clinical outcome parameters.<br>