Effect of vitamin C supplementation on children with Osteogenesis Imperfecta

Not Applicable

• Conditions: osteogenesis imperfecta; Q78.0

• Registration Number: RBR-65q4hg
• Lead Sponsor: niversidade do Sul de Santa Catarina

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-09-27
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Data analysis completed
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Patients with OI (types I, III and IV) and without other associated diseases. Age range from zero to 18 years. Patients who underwent intravenous disodium pamidronate treatment cycles at the HIJG every 2, 3, 4, or 6 months between January and December 2018. Patients who had conditions for oral medication administration. Patients who do not use continuous analgesics, continuous anti-inflammatory drugs or antidepressants for pain control or other medical indication.

Exclusion Criteria

PParticipants who did not attend the hospital for disodium pamidronate administration. Participants who presented temporary or permanent suspension of disodium pamidronate administration during the data collection period. Participants who did not have blood samples collected during the first or second data collection. Participants who did not return for the second data collection. Participants who used continuous analgesics, continuous anti-inflammatory drugs and antidepressants for pain control or other medical indication after the first data collection. Participants reporting inadequate vitamin C supplementation between data collections.

Study & Design

• Study Type: Intervention
• Study Design: Not specified