The Relationship Between Driving Pressure, Mechanical Power, Oxygenation and Saturation Indices: Retrospective Observational Study

Completed

• Conditions: Pneumonia; Acute Respiratory Distress Syndrome

• Registration Number: NCT05677165
• Lead Sponsor: Bakirkoy Dr. Sadi Konuk Research and Training Hospital

Brief Summary

By using Mechanical Power and Driving Pressure instead of Pmean we calculate new oxygen saturation indices like Driving Pressure Oxygen Index (OIDP), Dynamic Power Oxygen Index (OIMPdyn), Total Power Oxygen Index (OIMPtot), Driving Pressure Saturation Index (OSIDP), Dynamic Power Saturation Index (OSIMPdyn) ve Power Saturation Index (OSIMPtot).

New oxygenation and saturation indices are able to predict ICU mortality better than the conventional indexes and rates.

Detailed Description

Not available

Study Timeline

• Study Start: 2020-03-18
• Primary Completion: 2021-11-01
• Study Completion: 2021-11-28
• Study First Submitted: 2022-11-21
• Status Verified: 2022-12
• Study First Submitted QC: 2022-12-22
• Last Update Submitted: 2022-12-22
• Study First Posted: 2023-01-10
• Last Update Posted: 2023-01-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 361

Inclusion Criteria

• Patients with a diagnosis of Covid-19 related Acute Respiratory Syndrome (C-ARDS) which hospitalized in Bakirköy Dr. Sadi Konuk Training and Research Hospital intensive care unit

Exclusion Criteria

• Patients who did not receive invasive mechanical ventilation support.
• Patients who stayed in the intensive care unit for less than 24 hours.
• Patients with missing data
• Patients who received mechanical ventilation support for less than 24 hours
• Patients with Chronic Obstructive Pulmonary Disease (COPD).
• Patients with congestive heart failure
• Patients who underwent tube thoracostomy due to tension pneumothorax
• Patients who received Extracorporeal Membrane Oxygenation (ECMO) support

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
In hospital mortality	28 days	we estimate hospital mortality mortality by calculating new oxygenation index

Secondary Outcome Measures

Name	Time	Method
Mechanical ventilatory free days	30 days	we estimate hospital mortality mortality by calculating new saturation index

Trial Locations

Locations (1)

Bakirköy Dr sadi konuk Education hospital; 🇹🇷 Istanbul, Turkey