Influence of oxygen partial pressure in the evaluation of cerebrovascular carbon dioxide responsiveness

Completed

• Conditions: autonomic control; brainvessel chemoregulation; 10003216

• Registration Number: NL-OMON38776
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 20

Inclusion Criteria

Healthy (18-80 years old) and willing and realizing what it means to give informed consent.

Exclusion Criteria

Underlying cardiovascular diseases
Diabetes
Treatment with vasoactive agents

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Primary endpoint of this study is cerebrovascular CO2 reactivity quantified by<br /><br>cerebral blood flow velocity/cerebral oxygenation responses to CO2. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Systemic hemodynamics (blood pressure, heart rate, stroke volume, cardiac<br /><br>output and total peripheral resistance). </p><br>