NCT01949272已完成不适用
Optimization of PEEP for Alveolar Recruitment in ARDS
Hopital of Melun1 个研究点 分布在 1 个国家目标入组 22 人开始时间: 2013年9月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 22
- 试验地点
- 1
- 主要终点
- PaO2/FiO2 ratio
研究概览
简要总结
Actual setting of PEEP in ARDS is based on tables linked to FiO2, or respiratory system plateau pressure (e.g EXPRESS Study) or set regarding esophageal pressure mesurement and transpulmonary pressure calculation. Opera study should confirm if a setting approach based on esophageal pressure is helpfull for any ARDS patient in ICU without deleterious side-effect.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •ARDS Stades 2 and 3 with invasive ventilation (EXPRESS settings) within 3 to 12 hours
排除标准
- •less 18 years, pregnancy, intracardiac shunt, esophageal catheter cons-indicated
结局指标
主要结局
PaO2/FiO2 ratio
时间窗: 24 hours
次要结局
- Vd/Vt ratio(24 hours)
研究者
Sebastien Jochmans, MD
MD
Hopital of Melun
研究点 (1)
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