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Clinical Trials/NCT01949272
NCT01949272
Completed
Not Applicable

Optimization of PEEP for Alveolar Recruitment in ARDS

Hopital of Melun1 site in 1 country22 target enrollmentSeptember 2013
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ConditionsARDS

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
ARDS
Sponsor
Hopital of Melun
Enrollment
22
Locations
1
Primary Endpoint
PaO2/FiO2 ratio
Status
Completed
Last Updated
9 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

Actual setting of PEEP in ARDS is based on tables linked to FiO2, or respiratory system plateau pressure (e.g EXPRESS Study) or set regarding esophageal pressure mesurement and transpulmonary pressure calculation. Opera study should confirm if a setting approach based on esophageal pressure is helpfull for any ARDS patient in ICU without deleterious side-effect.

Registry
clinicaltrials.gov
Start Date
September 2013
End Date
May 2016
Last Updated
9 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Hopital of Melun
Responsible Party
Principal Investigator
Principal Investigator

Sebastien Jochmans, MD

MD

Hopital of Melun

Eligibility Criteria

Inclusion Criteria

  • •ARDS Stades 2 and 3 with invasive ventilation (EXPRESS settings) within 3 to 12 hours

Exclusion Criteria

  • •less 18 years, pregnancy, intracardiac shunt, esophageal catheter cons-indicated

Outcomes

Primary Outcomes

PaO2/FiO2 ratio

Time Frame: 24 hours

Secondary Outcomes

  • Vd/Vt ratio(24 hours)

Study Sites (1)

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