Optimization of PEEP for Alveolar Recruitment in ARDS
Completed
- Conditions
- ARDS
- Interventions
- Device: esophageal pressure mesurement
- Registration Number
- NCT01949272
- Lead Sponsor
- Hopital of Melun
- Brief Summary
Actual setting of PEEP in ARDS is based on tables linked to FiO2, or respiratory system plateau pressure (e.g EXPRESS Study) or set regarding esophageal pressure mesurement and transpulmonary pressure calculation. Opera study should confirm if a setting approach based on esophageal pressure is helpfull for any ARDS patient in ICU without deleterious side-effect.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 22
Inclusion Criteria
- ARDS Stades 2 and 3 with invasive ventilation (EXPRESS settings) within 3 to 12 hours
Exclusion Criteria
- less 18 years, pregnancy, intracardiac shunt, esophageal catheter cons-indicated
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description ARDS esophageal pressure mesurement ARDS patients achieving stades II and III of Berlin 2011 Classification
- Primary Outcome Measures
Name Time Method PaO2/FiO2 ratio 24 hours
- Secondary Outcome Measures
Name Time Method Vd/Vt ratio 24 hours
Trial Locations
- Locations (1)
Melun Hospital ICU
🇫🇷Melun, France