Effects of Music Training on Neurodevelopment and Associated Health Outcomes
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Music
- Sponsor
- University of Southern California
- Enrollment
- 114
- Locations
- 1
- Primary Endpoint
- brain inhibition control networks
- Status
- Active, not recruiting
- Last Updated
- 5 months ago
Overview
Brief Summary
This proposed study aims to provide a definitive answer to whether music training benefits brain development, particularly brain inhibition control circuitry and its related health outcomes using a randomized control trial design.
In the study, 114 children between ages 6-8 from Los Angeles will be randomly assigned to a 24-month:(1) community-focused after school music training group focused on a traditional strings curriculum at the Colburn school in Los Angeles (MG) or (2) a control group (CG) after-school program comprising of visual arts, book club, ethnic and cultural studies and theater without specific focus on systematic music training or sports. Imaging data will be collected at before and after the intervention (24 months), behavioral assessments will be conducted before the intervention and yearly afterwards, and mid-intervention evaluations will be performed every six months throughout the study.
Detailed Description
The investigators will use an RCT design to investigate effects of a music training intervention on brain inhibition control circuitry. Throughout R61(N=40) and R33 (N=74) phases, 114 children between ages 6-8 from communities with limited resources in Los Angeles will be randomly assigned to a 24-month: (1) community-focused after school music training group focused on a traditional strings curriculum at the Colburn school in Los Angeles (MG) or (2) a control group (CG) after-school program comprising of visual arts, book club, ethnic and cultural studies and theater without specific focus on systematic music training or sports. Imaging data will be collected at before and after the intervention (24 months), behavioral assessments will be conducted before the intervention and yearly afterwards, and mid-intervention evaluations will be performed every six months throughout the study. The investigators anticipate that the R61 phase will take 2 years and R33 will take 3 years to complete. The goal of the R61 phase is to evaluate the feasibility of executing the RCT. Comprehensive behavioral and imaging data will be collected at pre- and post-intervention, and mid-intervention evaluations will be performed every six months throughout the study. The combined R61/R33 phases will include 114 participants and will ultimately provide much needed guidance on the development of larger trials in the field.
Investigators
Assal Habibi
Associate Professor
University of Southern California
Eligibility Criteria
Inclusion Criteria
- •normal IQ (standard score of \>85 in the Abbreviated Wechsler's Scale of Intelligence)
- •Living in LA within 2 miles radius of the location of the music and the afterschool programs
- •limited resources as defined by the Hollingshead Index cumulative score below 29
Exclusion Criteria
- •current diagnosis of neurological or psychiatric disorders
- •prior engagement in formal and systematic music training for more than 6 months
- •previous or current diagnosis of severe hearing loss defined as air conduction thresholds greater than 60 dB HL through 8 kHz or- severe vision loss that is not correctable with prescription eyeglasses or contact lenses
- •non-removable, non-MRI compatible body parts
- •Claustrophobia
Outcomes
Primary Outcomes
brain inhibition control networks
Time Frame: 24 months
The primary outcome will be %change in blood-oxygen-level-dependent signal in the brain frontal circuits including the DLPFC, ACC and pre-SMA/SMA evaluated during the two inhibition control tasks.
Secondary Outcomes
- inhibition control as measured by delayed gratification(24 months)
- inhibition control as measured by reaction time(24 months)