Combined isobutylamido thiazolyl resorcinol and low-fluence Q-switched Nd:YAG laser for the treatment of melasma in Asians: a randomized, split-face study

Phase 3

Completed

• Conditions: laser; Reduction of melasma.; melasma; hyperpigmentation

• Registration Number: TCTR20200410010
• Lead Sponsor: Division of Dermatology, Department of medicine, Faculty of Medicine, Ramathibodi hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2020-03-16
• Study Start: 2020-04-10
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 25

Inclusion Criteria

Symmetrical mixed type melasma on both malar areas

Exclusion Criteria

Pregnant or lactating women
Having a dermatological condition on the treating area
History of topical or systemic therapy for melasma within 1 mont
History of laser therapy within 6 months

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
mean relative lightness index evaluate at every visit colorimeter (DSM II ColorMeter®),Clinical changes evaluate at every visit Melasma Area and Severity Index on the malar area (MASIm),patient satisfaction scores evaluate at every visit visual analogue scale on improvement of melasma

Secondary Outcome Measures

Name	Time	Method
Adverse events evaluate at every visit Dermatologist evaluation and patients' feedback