Effect of three concentrations of oxygen used during operation on immunity in patient undergoing surgery for benign thyroid – An experimental study
Not Applicable
- Conditions
- Health Condition 1: D34- Benign neoplasm of thyroid gland
- Registration Number
- CTRI/2022/07/043909
- Lead Sponsor
- Department of Health Research
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Inclusion criteria
1.ASA I, II patients,
2.Body mass index between 18-30 kg/m2,
3.Patients posted for surgery for benign thyroid conditions will be included in this study.
Exclusion Criteria
Exclusion criteria
1.Patients refusal to participate in the study,
2.Perioperative blood transfusions,
3.Chronic opioid use,
4.Renal failure,
5.Liver failure,
6.Congestive heart failure and
7.Hematological diseases will be excluded from the study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary end point of the study will be effect of different FiO2 on NK cell count (CD56, CD6)Timepoint: Perioperative
- Secondary Outcome Measures
Name Time Method The secondary end points will be effect of different FiO2 on <br/ ><br>a.The total T lymphocyte count and counts for the T lymphocyte subpopulations, CD3, CD4, CD8, CD19, Th1 and Th2cells. <br/ ><br>b.Postoperative complications in patients undergoing surgery for thyroid surgeries. <br/ ><br>Timepoint: Perioperative