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临床试验/RBR-446krjm
RBR-446krjm尚未招募未知

Impact of Prebiotic Polydextrose as an Adjunct in the Treatment of Periodontitis and Modulation of Subgingival and Intestinal Microbiomes

niversidade de São Paulo0 个研究点开始时间: 2022年3月4日最近更新:
适应症

试验速览

阶段
未知
状态
尚未招募
发起方

研究概览

简要总结

暂无简介。

研究设计

研究类型
Intervention

入排标准

年龄范围
18Y 至 70Y(—)

入选标准

  • Presence of at least 15 natural teeth, excluding third molars and teeth indicated for extraction; diagnosis of generalized stage III grade A and B periodontitis, with at least 30% of the teeth with at least one site with probing depth and clinical level of insertion greater than or equal to 5 mm and bleeding on probing.

排除标准

  • Presence of other systemic conditions which can affect the progression of periodontitis or the response to its treatment; long-term administration of anti-inflammatory or immunosuppressive medication; periodontal treatment and / or use of antimicrobials in the last 6 months; use of probiotics in the last 6 months; continuous use of mouthwashes containing antimicrobial agents in the last 6 months; need for prophylactic antibiotic therapy for routine dental procedures; extensive prosthetic rehabilitation; tobacco consumption in the last 5 years; pregnancy and lactation and gastrointestinal diseases.

研究者

发起方
niversidade de São Paulo

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