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A Study Of Valsartan Used To Treat Hypertension For Up To 13 Months In Hypertensive Children Ages 6 - 16 Years Of Age

Phase 3
Completed
Conditions
Hypertension
Registration Number
NCT00171041
Lead Sponsor
Novartis
Brief Summary

Drugs used to treat high blood pressure in adults should also be effective in treating high blood pressure in children and adolescents. This study will test the safety and efficacy of valsartan in treating high blood pressure in hypertensive children 6-16 years of age whose parent(s)/guardian(s) grant permission to participate.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
265
Inclusion Criteria
  • CHILDREN HAVE SYSTOLIC BLOOD PRESSURE AT A LEVEL =>95th PERCENTILE FOR AGE/GENDER/HEIGHT
  • CONSENT FROM PARENT(S)/GUARDIAN(S) MUST BE GRANTED
Exclusion Criteria
  • BLOOD PESSURE IS =>5% HIGHER THAN 99th PERCENTILE FOR AGE
  • SERIOUS, CLINICALLY SIGNIFICANT FINDINGS UPON PHYSICAL EXAMINATION, AND LABORATORY AND OTHER ASSESSMENTS

Other protocol-defined inclusion/exclusion criteria will also apply.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Change from baseline in sitting systolic blood pressure after 2 weeks
Secondary Outcome Measures
NameTimeMethod
Change from baseline diastolic blood pressure after 2 weeks
Change from baseline systolic blood pressure after 4 weeks
Change from baseline diastolic blood pressure after 4 weeks
Change from baseline systolic and diastolic blood pressure after 4 weeks and 52 weeks
Change in diastolic blood pressure after 2 weeks to 4 weeks

Trial Locations

Locations (1)

Novartis Pharmaceuticals

🇺🇸

E.Hanover, New Jersey, United States

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