The Effect of CoQ10 Administration on Hemodialysis Patients

Phase 4

Completed

• Conditions: Chronic Renal Failure; Hemodialysis

• Registration Number: NCT00307996
• Lead Sponsor: University of Shizuoka

Brief Summary

The purpose of this study is to examine whether CoQ10 administration is effective as an antioxidant in hemodialysis patients.

Detailed Description

Oxidative stress has been recognized as a potential risk factor for such complications as atherosclerosis in hemodialysis patients. This study investigates whether CoQ10 administration is effective for protecting oxidative stress in hemodialysis patients. The subjects were recruited from day-time hemodialysis patients in Iwata City Hospital. 100 mg CoQ10 was administered every HD for 6 months. Several oxidative and antioxidative markers were measured in plasma at pre, 1, 3, 6 months and after washout.

Study Timeline

• Study Start: 2004-03
• Study Completion: 2004-12
• Status Verified: 2006-03
• Study First Submitted: 2006-03-27
• Study First Submitted QC: 2006-03-27
• Last Update Submitted: 2006-03-27
• Study First Posted: 2006-03-28
• Last Update Posted: 2006-03-28

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• hemodialysis for at least 6 months

Exclusion Criteria

• none

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Oxidative protein concentration at 6 month
Antioxidant capacity at 6 month

Trial Locations

Locations (1)

Iwata City Hospital; 🇯🇵 Iwata, Shizuoka, Japan