临床试验/NCT00307996

NCT00307996已完成4 期

The Effect of CoQ10 Administration on the Oxidative and Antioxidative Markers in Hemodialysis Patients

University of Shizuoka2 个研究点分布在 1 个国家目标入组 40 人开始时间: 2004年3月最近更新: 2006年3月28日

适应症

试验速览

阶段: 4 期
状态: 已完成
发起方: University of Shizuoka
入组人数: 40
试验地点: 2
主要终点: Oxidative protein concentration at 6 month

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

The purpose of this study is to examine whether CoQ10 administration is effective as an antioxidant in hemodialysis patients.

详细描述

Oxidative stress has been recognized as a potential risk factor for such complications as atherosclerosis in hemodialysis patients. This study investigates whether CoQ10 administration is effective for protecting oxidative stress in hemodialysis patients. The subjects were recruited from day-time hemodialysis patients in Iwata City Hospital. 100 mg CoQ10 was administered every HD for 6 months. Several oxidative and antioxidative markers were measured in plasma at pre, 1, 3, 6 months and after washout.

研究设计

研究类型: Interventional
分配方式: Non Randomized
干预模型: Single Group
主要目的: Treatment
盲法: None

入排标准

年龄范围: 0 Years 至 85 Years（Child, Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

•hemodialysis for at least 6 months

排除标准

未提供

结局指标

主要结局

Oxidative protein concentration at 6 month

Antioxidant capacity at 6 month

次要结局

未报告次要终点

研究者

发起方

University of Shizuoka

申办方类型

Other

研究点 (2)

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