Feasibility of Computed Tomography Derived Myocardial Blood Flow Using Whole-Heart Dynamic Computed Tomography Perfusion Imaging: Differentiation of Myocardial Ischemia and Infarction Assessed by Comparison with Cardiac Magnetic Resonance and Single Photon Emission Computed Tomography
Not Applicable
- Conditions
- Coronary artery disease
- Registration Number
- JPRN-UMIN000015964
- Lead Sponsor
- Ehime University Graduate School of Medicine.
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Not provided
Exclusion Criteria
(1) acute myocardial infarction (2) cardiomyopathy (3) severe left ventricular dysfunction (ejection fraction < 20%) (4) chronic atrial fibrillation (5) greater than first degree atrio-ventricular block (6) symptomatic congestive heart failure of New York Heart Association class IV (7)percutaneous coronary intervention (8) history of coronary artery bypass graft (9) hypotension (systolic blood pressure < 90 mm Hg) (10) severe chronic obstructive pulmonary disease (11) chronic kidney disease (serum creatinine > 1.5 mg/dl) (12) pregnancy (13) known history of hyperthyroidism and bronchial asthma (14) known hypersensitivity to contrast media.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Differentiation of CT-derived MBF among normal, ischemic and infarcted myocardium in patient groups of SPECT and cardiac MR, respectively. Diagnostic accuracy of CT-derived MBF for detecting myocardial perfusion abnormality on SPECT and cardiac MR.
- Secondary Outcome Measures
Name Time Method