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Diaphragmatic Ultrasound and Thoracic Fluid Content for Prediction of Non-Invasive Ventilation Failure in Neonates

Completed
Conditions
Diaphragm Ultrasound
Electrical Cardiometry
Non Invasive Ventilation (NIV)
RDS of Prematurity
Registration Number
NCT07148102
Lead Sponsor
Lamiaa Khaled Zidan
Brief Summary

This research assessed diaphragmatic ultrasound and thoracic fluid content (TFC) as potential early predictive tools for detecting NIV failure in preterm neonates.

Detailed Description

Non-invasive ventilatory support (NIV) is considered a gold standard care for preterm infants with respiratory distress syndrome (RDS); however, NIV failure remains a frequent challenge that is often associated with many adverse outcomes

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
90
Inclusion Criteria
  • Preterm neonates of both sexes, with gestational ages ranging from 28 to 34 weeks, diagnosed with RDS and requiring non-invasive ventilation within 30 minutes of birth
Exclusion Criteria
  • Exclusion criteria included intubation in the delivery room, complex congenital heart disease, major congenital anomalies in the lungs or airways, and other causes of respiratory distress unrelated to RDS.

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The predictive valueTwo years

The predictive value of DTF, DE, and TFC for NIV failure in preterm neonates with RDS.

Secondary Outcome Measures
NameTimeMethod
Success RateTwo years

Comparing success rates among CPAP, NIPPV, and NHFOV groups,

Trial Locations

Locations (1)

Faculty of Medicine, Tanta University

🇪🇬

Tanta, Tanta, Q2x2+cp Tanta 2, Egypt, Egypt

Faculty of Medicine, Tanta University
🇪🇬Tanta, Tanta, Q2x2+cp Tanta 2, Egypt, Egypt

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