Study effect of dexmedetomidine drug during laparoscopic cholecystectomy

Completed

• Conditions: Calculus of gallbladder with acutecholecystitis,

• Registration Number: CTRI/2020/07/026594
• Lead Sponsor: Pt B DSHARMA PGIMS ROHTAK

Brief Summary

The present prospective study will be conducted in the depatment of anaesthesia and critical care,PGIMS,ROHTAK.Written informed consent will be taken from patients included.The study is to investigate the effect of dexemedetomidine on hemodynamic response in untreated stage1 hypertensive patients undergoing laproscopic cholecystectomy.The changes in HR & MAP during laryngoscopy,intubation,creation & release of pneumoperitonium and extubation will be noted.Data will be compiled and analysed with appropriate statistical test.

Detailed Description

Not available

Study Timeline

• Study Start: 2020-07-17
• Study Completion: 2021-03-29
• Last Update Posted: 2021-10-08

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Asa 1&2 Either sex Posted for laproscopic cholecystectomy Stage 1 hypertensive patients,not on any medication.

Exclusion Criteria

Patients with difficult airway Stage 2 hypertensive Patients on antihypertensive medication Patients with cardiac,renal,hepatic or endocrine disease Pregnant or morbid obese Allergic to dexmedetomidine.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To investigate effect of dexmedetomidine on hemodynamic response to laryngoscopy,intubation,pneumoperitoneum and extubation in stage 1 hypertensive patients undergoing laproscopic cholecystectomy	To investigate effect of dexmedetomidine on hemodynamic response to laryngoscopy,intubation,pneumoperitoneum 15 minutes,release of pneumoperitoneum and extubation in stage 1 hypertensive patients undergoing laproscopic cholecystectomy during perioperative period.

Secondary Outcome Measures

Name	Time	Method
To observe time to extubate trachea,time to first rescue analgesia and post operative sedation score at 1 min, 15 minutes, 30 minutes and 60 minutes.	Any adverse effects like hypotension,bradycardia and excessive sedation during perioperative period and sedation score at 1 minute, 15 minute,30 minutes and 60 minutes.

Trial Locations

Locations (1)

Pt BD Sharma PGIMS, Rohtak; 🇮🇳 Rohtak, HARYANA, India

Pt BD Sharma PGIMS, Rohtak

🇮🇳Rohtak, HARYANA, India

Dr Sudesh Kumar

Principal investigator

07988818847

dr.sudeshkr@gmail.com