Investigation the effect of hull-less barley bread on lipid profile, fasting blood sugar and effective factors on vascular endothelial function in hypercholestrolemic patients
Not Applicable
- Conditions
- Hypercholesterolemic.Low-density-lipoprotein-type [LDL] hyperlipoproteinaemia
- Registration Number
- IRCT201312073733N3
- Lead Sponsor
- Isfahan Cardiovascular Research Institute
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Age 25-65 years old; hypercholesterolemia patients who receiving statins for hypercholesterolemia.
Exclusion criteria: Diabetes type one or two; hypothyroidism; renal failure; anemia; cholestasis; pancreatic cancer or malignancy; secondary dyslipidemia; used antihypertensive drugs; alcohol; smoked; did regular exercise; had a history of eating disorder; had weight changes (losing or gaining more than three kilogram weight during the three months prior to the study)
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ipid Profile. Timepoint: Before and after intervention. Method of measurement: Autoanalyzer.;Fasting blood sugar. Timepoint: Before and after intervention. Method of measurement: Autoanalyzer.;Flow-mediated dilation (FMD). Timepoint: Before and after intervention. Method of measurement: FMD is a noninvasive technique where forearm ischemia is induced by inflating a sphygmomanometer cuff to 50-100 mmHg for five minutes.
- Secondary Outcome Measures
Name Time Method Body mass index. Timepoint: before and after intervention. Method of measurement: Body mass index (BMI) was calculated as weight divided by height squared.;Hip circumference. Timepoint: before and after intervention. Method of measurement: measured based on standard protocols.;Waist circumference. Timepoint: before and after intervention. Method of measurement: measured based on standard protocols.;Blood pressure. Timepoint: before and after intervention. Method of measurement: after 20-minuterest, in sitting position.