Comparison of effect of oral Utrogestan and intramascular Proluton on Maternal and fetal Doppler circulatuion in women with preterm labor risk
Phase 3
Recruiting
- Conditions
- Preterm labor.Preterm labor without delivery, unspecified trimesterO60.00
- Registration Number
- IRCT20200201046324N1
- Lead Sponsor
- Kashan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 152
Inclusion Criteria
Single pregnancy with gestational age of 20-34 weeks based on LMP and ultrasound confirmation who presented with pain and consent to participate in the study
Cervical length shortening (less than 25 mm)
No rupture of membrane
Preterm labor history
Experience regular uterine contractions at least one occasion leading to an episode of hospitalization for preterm labor
Changes in cervical dilatation or effacement confirmed by vaginal ultrasound
No maternal hypertension
Exclusion Criteria
No follow-up for Doppler ultrasound
No proper use of medications
Known fetal anomaly and fetal death
Tocolytic therapy
Progesterone allergy
Indications of rapid labor such as fetal distress or severe bleeding
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pulsatility Index (PI). Timepoint: At baseline and 48 hours later. Method of measurement: Abdominal ultrasound transducer 2-5 MHz.
- Secondary Outcome Measures
Name Time Method