Effects of acute ketamine administration on mental representations of the body in healthy participants.

Not Applicable

Withdrawn

• Conditions: Schizophrenia; Mental Health - Studies of normal psychology, cognitive function and behaviour

• Registration Number: ACTRN12611000197932
• Lead Sponsor: Prof. Mathew Martin-Iverson

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2011-02-21
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Withdrawn
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

Healthy participants

Exclusion Criteria

1. Pregnancy or currently breastfeeding
2. Neurological disorders or known seizure risk
3. History of loss of consciousness for over 5 mins
4. Current diagnosis or treatment for a mental illness
5. Past or current treatment for substance use disorder
6. Significant risk of psychoses (previous history of psychosis or first-degree relative diagnosed with schizophrenia/schizophrenia-spectrum disorders)
7. Presence or history of a kinetic disorder
8. Presence or history of hypertension
9. Presence or history of hepatic insufficiency
10. Presence of renal insufficiency
11. Presence or history of cardiovascular disorder
12. Significant risk of suicide
13. Known hypersensitivity to ketamine
14. Receiving any systematic prescription medication (excluding oral contraceptive pill)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Proprioceptive Drift in the Projected Hand Illusion[20 mins after initial dosing];Subjective Experience of the Projected Hand Illusion Questionnaire[30 mins after initial dosing]

Secondary Outcome Measures

Name	Time	Method
Plasma ketamine level[0 and 90 mins after initial dosing]