Chest Mobility, Strength, Physical Activity and Quality of Life in Parkinson's Patients With Post-COVID-19

Completed

• Conditions: COVID-19 Respiratory Infection; Parkinson Disease

• Registration Number: NCT06008444
• Lead Sponsor: Izmir Democracy University

Brief Summary

To comparative pain intensity, chest mobility, cough strength, muscle strength, physical activity levels and quality of life in Parkinson's patients with post-COVID-19 and without post-COVID-19 was aimed in current study. Knowledge in the literature regarding this topic is still obscure.

Detailed Description

Acute worsening and long-term sequelae of motor and non-motor symptoms have also been described in Parkinson's patients during and after SARS-CoV-2 infection, which is also known as prolonged COVID. The effects of COVID-19 on pain, chest mobility, cough strength, muscle strength, physical activity levels and quality of life in Parkinson's patients are still unclear today. For this reason, in this study, it was aimed to comparatively investigate pain, chest mobility, cough strength, muscle strength, physical activity levels and quality of life in Parkinson's patients with COVID-19 and without COVID-19 and to show the relationships between these outcome measures.

Study Timeline

• Study Start: 2023-05-13
• Study First Submitted: 2023-08-21
• Study First Submitted QC: 2023-08-22
• Study First Posted: 2023-08-23
• Primary Completion: 2024-08-30
• Study Completion: 2024-12-30
• Status Verified: 2025-05
• Last Update Submitted: 2025-05-16
• Last Update Posted: 2025-05-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 32

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Total quality of life score evaluated by Parkinson's Disease Questionnaire (PDQ-39) questionnaire.	through study completion, an average of 1 year	The status of quality of life will be evaluated using Parkinson's Disease Questionnaire (PDQ-39) questionnaire. Parkinson's Disease Questionnaire-39 (PDQ39) is a 39-item quality of life questionnaire. Evaluation for each question item ranges from 0 (no problem) to 4 (constant problem). Low scores in total indicate an improvement in people's quality of life.

Secondary Outcome Measures

Name	Time	Method
Chest mobility	through study completion, an average of 1 year	Chest mobility will be evaluated using a tape measure.
Cough Strength	through study completion, an average of 1 year	Cough Strength will be evaluated using a Peak Flow Meter.
Daily average step count	through study completion, an average of 1 year	Daily average step counts will be recorded via a pedometer everyday within 3 days after confirming enrolment. All individuals will be asked to carry their pedometers with them during the day and record to their diaries.
Hand grip strength	through study completion, an average of 1 year	Hand grip strength will be evaluated using a hand dynamometer.
Cognitive status	through study completion, an average of 1 year	Cognitive state will be evaluated using The mini-mental state examination (MMSE). It is an 11 question test. The highest score from the test is 30 points. Scores of 23 and lower indicate cognitive dysfunction, and scores of 24 and higher indicate normal cognitive level.

Trial Locations

Locations (1)

Izmir Democracy University; 🇹🇷 İzmir, Turkey